Time Slaughter

Released in 1996 for the DOS, Timeslaughter is a fighting game made by the largely comedic Bloodlust Software, made partly to make fun of the surge of violent fighting games that followed Mortal Kombat.
Scientist William Spade is very close to completing a fully functional time machine, but has little time to celebrate when four members of a race of time-worshipping demons known as the Takar pay him a visit. Staine, the Dreg, the Surgeon, and the Butcher torture Spade within an inch of his life after he refuses to surrender the time machine before its completion. After losing both arms and his left eye, Spade manages to activate the time machine with his nose, sending the Takar back to where they came from, but causes a huge rip in the timestream in the process due to prematurely activating the machine.
As a result, combatants from unique time periods are zapped randomly from place to place, each with their own reason to fight - none of them knowing where they will go next. Spade rebuilds his body, renaming himself Portal, and is now more than ready to defend himself from anyone who might be warped to his plane of existence — including the Takar.
Under the frankly ugly graphics, the core of Timeslaughter is surprisingly good if you consider it was made by just two people. A shareware Fighting Game offering multiparallax backgrounds, 3D floors, a ton of digitized speech, blood that stayed on the ground, visible damage on the fighters, several levels of difficulty and speed... and was also quite smooth to play, wasn't really something you saw all days on DOS in the mid 1990s, unless you were dealing with the official conversions of Super Street Fighter II Turbo and the earlier episodes of Mortal Kombat.
Although it was originally sold, the game and a "director's cut" version (really just a functioning beta with some different art assets) is now freeware.
A sequel was in the making but, due to Real Life schedules of the authors, it's unlikely it will ever see the light.